Pneumocystis Melanins Confer Enhanced Organism Viability
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چکیده
منابع مشابه
Pneumocystis carinii: an atypical fungal micro-organism.
The purpose of this review is to assist mycologists in having a better understanding of Pneumocystis carinii and the disease that it causes. Now considered to be a fungus, P. carinii is unusual in its life cycle and relationship with the host. P. carinii pneumonia (PCP) pathogenesis, immunology and host defence mechanisms are examined, as well as epidemiological and control strategies. Most pne...
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Melanins represent virulence factors for several pathogenic fungi; the number of examples is growing. Thus, albino mutants of several genera (in one case, mutated precisely in the melanizing enzyme) exhibit decreased virulence in mice. We consider the phenomenon in relation to known chemical properties of melanin, beginning with biosynthesis from ortho-hydroquinone precursors which, when oxidiz...
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ژورنال
عنوان ژورنال: Eukaryotic Cell
سال: 2006
ISSN: 1535-9778,1535-9786
DOI: 10.1128/ec.00176-05